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Mezcal Negroni Cocktail

5 from 2 votes
Sharon BestBy Sharon Best
Sharon Best
Sharon Best Food Editor

Personable freelance writer and insatiable foodie, dedicated to excellent prose and mind-blowing culinary experiences.

Expertise: Editorial Food Content, Creative Composition View all posts →
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Bring extra depth and smokiness to cocktail hour with this easy recipe for the Negroni’s Mexican cousin that swaps gin for mezcal!

Love the bold bitterness and elegance of a classic gin-laced Negroni? Looking for something similar but a little deeper, darker, and smokier? Prepare your taste buds for that Italian cocktail’s Mexican cousin—the mezcal Negroni.

Swapping gin for mezcal in a Negroni does more than just change the spirit—it transforms the entire character of the cocktail. The signature smoky edge and earthy agave undertones of mezcal bring depth and rustic complexity to the classic mix of bitter Campari and sweet vermouth. Mezcal’s smokiness is the result of roasting agave hearts in underground pits, a traditional practice that imparts notes of caramelized agave, toasted spice, and campfire to the spirit. In this mezcal Negroni recipe, these bold smoky flavors complement rather than overpower, mingling harmoniously with bittersweet and citrus elements for a uniquely satisfying sipping experience.

Campari is considered an acquired taste. It delivers flavors of orange, cherry, herbal spice, bitters, and peppery complexity. Sweet vermouth contributes fullness of body to the drink, along with notes of caramel, vanilla, cocoa, and dried dark cherries.

Together, these three ingredients become a captivating blend of smoke, herbal citrus, and dark fruit—with each sip revealing new layers of flavor.

Ingredient spotlight: Campari

Gaspare Campari invented the Italian bitter liqueur that bears his name in 1860. Classified as an aperitivo—aka a pre-meal drink meant to stimulate appetite—it’s known for its vivid ruby-red color and distinctive bittersweet flavor profile. The exact recipe is a closely guarded secret, but confirmed and widely reported ingredients include bitter orange peel, rhubarb, quinine, ginseng, chinotto (a citrus fruit), and cascarilla bark, as well as various other herbs, aromatic plants, and fruits that are macerated in a mixture of alcohol and water. Campari’s original red color came from cochineal insects, but it’s been produced with artificial colorants since 2006. The liqueur is a signature ingredient in classic cocktails like the Negroni, Americano, and Jungle Bird.

How do I store leftovers?

Store leftover mezcal Negronis in an airtight container in the fridge or freezer for up to 1 month. A refrigerated drink may taste less vibrant after 3-4 weeks but remains safe to drink. The high alcohol content prevents this cocktail from freezing solid, and storing in the freezer prevents oxidation and keeps flavors lively—so freezing is a great option for both leftovers and make-ahead batches. Simply pour directly from the freezer over fresh ice, stir, garnish, and serve.

Serving suggestions

Serve mezcal Negronis alongside rich, smoky, or spicy dishes that can stand up to the drink’s bold flavor profile. Start with a Smoked Salmon Appetizer, then move on to Carnitas or Smoky And Sweet Gluten-Free Turkey Chili for the main course. Finish with a bittersweet dessert, like these Chocolate Truffles.

Recipe

Mezcal Negroni Cocktail

5 from 2 votes
Print Rate
Serves: 1
Prep: 3 minutes minutes
Total: 3 minutes minutes

Ingredients

  • 1 ounce mezcal
  • 1 ounce Campari
  • 1 ounce sweet vermouth
  • An orange wheel or twist optional, for garnish

Instructions

  • Combine the mezcal, Campari, and sweet vermouth in a mixing glass.
  • Fill the glass with ice and stir until the mixture is well chilled and slightly diluted, about 20 to 30 seconds.
  • Strain into a rocks glass over a large ice cube or fresh ice.
  • Garnish with an orange wheel or an expressed orange twist and serve right away.

Nutrition Info:

Calories: 107kcal (5%) Carbohydrates: 8g (3%) Sugar: 1g (1%)

Nutrition Disclaimer

Nutrition information are estimates only and may vary based on the specific brands, ingredients, and portion sizes you use. This data is provided for informational purposes only.

Author: Sharon Best
Course:Cocktails
Cuisine:American, Italian-Inspired, Mexican
Share your creationsTag @foodfaithfit and hashtag it #foodfaithfitness so I can see what you made!
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Woman smiling outdoors, enjoying healthy lifestyle and fitness, with a backpack and casual attire, under a modern roof structure.

About Sharon BestEditorial Food Content, Creative Composition

Personable freelance writer and insatiable foodie, dedicated to excellent prose and mind-blowing culinary experiences.

Reader Interactions

Paola Westbeek

✓Reviewed by Paola WestbeekGastronomy & Fine Wines

Published: Mar 4, 2024 | Updated: Mar 30, 2026
5 from 2 votes (2 ratings without comment)

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