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+ servings
Buffalo chicken casserole in a white baking dish, with penne pasta, melted cheese, and green onions.

Ingredients

  • 8 ounces whole grain penne pasta
  • 1 1/2 pounds boneless skinless chicken breasts, cut into 1/2-inch cubes
  • 1/2 teaspoon salt
  • 1/4 teaspoon black pepper
  • 1 teaspoon garlic powder
  • 3/4 teaspoon onion powder
  • 3/4 teaspoon smoked paprika
  • Neutral oil, for cooking chicken
  • 1 1/4 cups Buffalo wing sauce
  • 8 ounces low-fat cream cheese, softened
  • 1/3 cup low-fat ranch dressing
  • 3/4 cup plain Greek yogurt
  • 1 cup shredded mozzarella cheese
  • 2 cups shredded cheddar cheese
  • Green onions, thinly sliced for garnish

Instructions

  • Preheat your oven to 375°F. Grease a 9x13-inch baking dish. Boil salted water and cook pasta until al dente, then drain.
    Cooked penne pasta in a pot for buffalo chicken casserole.
  • Season the chicken cubes with salt, pepper, garlic powder, onion powder, and smoked paprika. In a large skillet over medium heat, heat a small amount of oil and sauté the chicken pieces until they are fully cooked, reaching an internal temperature of 165°F. Set aside.
    Juicy, tender chicken cooking in a white skillet with butter and spices, perfect for healthy recipes and meal prep.
  • In a bowl, whisk Buffalo wing sauce, cream cheese, ranch dressing, and Greek yogurt until smooth.
    Whisking creamy buffalo sauce for buffalo chicken casserole.
  • Combine the browned chicken and drained pasta with the sauce. Stir gently until everything is well-coated, then add in the shredded mozzarella cheese and mix to combine.
    Juicy chicken, cooked pasta, and creamy sauce in a skillet, healthy meal prep for balanced fitness and nutrition.
  • Transfer the mixture into the prepared baking dish. Sprinkle the shredded cheddar cheese evenly on top. Bake in the preheated oven for 25-30 minutes until the casserole is bubbly and the cheese is melted.
    Sprinkling shredded cheddar cheese on Buffalo Chicken Casserole before baking.
  • Remove the casserole from the oven. Garnish with sliced green onions and serve warm.
    Baked buffalo chicken casserole with penne pasta, melted cheese, and green onions.

Nutrition Info:

Calories: 623kcal (31%) Carbohydrates: 35g (12%) Protein: 48g (96%) Fat: 31g (48%) Saturated Fat: 14g (88%) Sodium: 2489mg (108%) Fiber: 1g (4%) Sugar: 5g (6%)

Nutrition Disclaimer

Nutrition information are estimates only and may vary based on the specific brands, ingredients, and portion sizes you use. This data is provided for informational purposes only.