Add the ground beef, chopped onion, and bell peppers to a large skillet over medium heat. Cook until the beef is browned and the onion is soft, breaking up the meat as it cooks.
Stir in the baked beans, brown sugar, ketchup, Worcestershire sauce, smoked paprika, mustard, garlic powder, salt, and pepper until well mixed.
Pour the mixture into a greased 9×13-inch baking dish and bake uncovered for 70-75 minutes, or until bubbly and heated through. Let stand for a few minutes before serving.